inadequate secretion of, or resistance to the effects of, antidiuretic hormone (ADH or Vasopressin). This hormone stimulates the kidney retain water in the body. Consequently, the dog passes a large volume of urine with a low specific gravity, and also exhibits great thirst. It may be acquired, inherited, or idiopathic. mellitus – due to a failure of the pancreas to produce sufficient insulin, or the cells resistance to the effects of insulin the body is unable to properly process glucose. May require insulin injections or may be controlled with diet. May be acquired or possibly inherited.